Lab for Clinical & Integrative Neuroscience

Advancing our understanding of brain function and dysfunction through innovative research at Trinity College Dublin

About Our Lab

Neuroscience Research

Our Mission

The lab for Clinical and Integrative Neuroscience (lab CLINT) is part of the Trinity College Institute for Neuroscience at Trinity College Dublin. Our mission is to deepen understanding of human brain function and translate this knowledge into better treatments for psychiatric and neurological disorders.

We combine advanced multimodal brain imaging with innovative invasive and non-invasive neuromodulation approaches to uncover the mechanisms of neuroplasticity dysfunction. In particular, we study how adaptive and maladaptive plasticity shape brain health and disease, with the goal of developing new therapies for neurological conditions such as chronic pain, tinnitus, Parkinson’s disease, and cognitive impairment, as well as psychiatric disorders including addiction, OCD, and depression.

Cutting-edge Research
Advanced Brain Stimulation

Research Areas

Clinical Neuroscience

Studying specific neurological and psychiatric disorders to develop biomarkers and novel therapeutic approaches.

Brain plasticity

Understanding the brain’s capacity for change — its neural plasticity — in both adaptive and maladaptive contexts.

Neuromodulation

Developing personalized neuromodulation treatment strategies for specific specific neurological and psychiatric conditions.

Recent Publications

Updated trends in the global prevalence and burden of mental disorders, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023

Published in The Lancet, 2026

A global analysis reveals that mental disorders are rising worldwide, placing a growing and unequal burden on health systems and communities.

 

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Tinnitus

Published in Nature Reviews Disease Primers, 2026

This study reframes tinnitus as more than “ringing in the ears”: a common, complex brain–ear disorder shaped by hearing injury, neural plasticity, stress and comorbidities, while pointing toward more personalized diagnosis and emerging treatments.

 

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More News

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Textbook of Tinnitus

The Textbook of Tinnitus (2nd edition), with contributions from the lab CLINT team, provides a comprehensive overview of the mechanisms, diagnosis, and treatments, reflecting major advances in tinnitus research.

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BRAI3N

BRAI3N clinic is implementing novel treatments developed at lab CLINT by translating our scientific findings into personalized, innovative therapies to treat specific neurological and psychiatric conditions.

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TIDE consortium

The goal of consortium is to develop an objective, AI-based biomarker for diagnosing tinnitus, advancing patient care and enabling investment from the pharmaceutical and hearing technology industries.

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Get In Touch

We welcome collaborations, student inquiries, and research partnerships. Reach out to learn more about our work.

Location

Trinity College Institute of Neuroscience - Lloyd Building

The University of Dublin - Trinity College Dublin

College Green

Dublin

Ireland

Email

lab.CLINT@tcd.ie