The Lab for Clinical and Integrative Neuroscience (Lab CLINT) is part of Trinity College Institute for Neuroscience at Trinity College Dublin. Lab CLINT aims to advance fundamental knowledge of human brain function and to use this knowledge to help people with psychiatric and neurological disorders. Our research integrates multimodal brain imaging techniques with novel invasive and non-invasive neuromodulation techniques to determine mechanisms underlying neuroplasticity dysfunction. More specifically, we work to understand the mechanisms of (mal)adaptive plasticity and develop new treatment approaches for different neurological (pain, tinnitus, Parkinson's disease, cognitive impairment) and psychiatric diseases (addiction, OCD, depression).
We are recruiting for a clinical trial on amnestic Mild Cognitive Impairment (aMCI) and Alzheimer's disease. The study is supported by Trinity College’s Institute of Neuroscience, The Global Brain Health Institute (GBHI), and The Alzheimer’s Association. Additionally, the Alzheimer's Society of Ireland and TeamUp for Dementia Research are supporting recruitment efforts. Our study is investigating whether we can modify brain networks to improve memory in individuals with aMCI.
More information: Clinical Trial
This book describes the theoretical background of the different forms of tinnitus (ringing in the ears) and detailed knowledge of state-of-the-art treatments of tinnitus. Textbook of Tinnitus has filled a void by providing a comprehensive overview about the different forms of tinnitus, their pathophysiology and their treatment. However, since the publication of the first edition of the Textbook of Tinnitus in 2011, tinnitus research has dramatically evolved. In view of the substantial increase in knowledge, most chapters in this second edition are newly written and a few original chapters have had major updates. This edition has nine sections, covering the basics of tinnitus, the neurobiology of tinnitus, pathophysiological models, animal research, diagnosis and assessment, various forms of management and treatment, and finally, a look at the future of tinnitus and tinnitus research.
Tinnitus Éire is an association for people with lived experience of tinnitus. Here, we learn more about tinnitus, discuss latest developments in tinnitus research and clinical practice and get together as a community to sing, dance and build peer support and camaraderie through the arts. If you wish to join this community and receive updates on our event you can follow the link below.
More information: website
The overarching goal of the TIDE consortium is to develop an objective method for diagnosing tinnitus. We will use different approaches for measuring brain activity and will analyze the results by means of artificial intelligence to identify a marker that can tell if a person hears tinnitus or not. The development of a biomarker in tinnitus would be ground-breaking and disruptive at the same time. It would advance patient management on a new level. By deriving two test paradigms from the most recent models of tinnitus, unpacking it in terms of depth of detail and breadth of application, and deploying it to explain wider aspects of the phenomenon than just the initial emergence of tinnitus, we seek for an objective marker for tinnitus or at least for a subtype of tinnitus related to a specific pathophysiology. This may have a major impact and fill the need of the pharmaceutical and hearing tech industry for biomarkers they require to start investing in tinnitus.
More information: TIDE
The Tinnitus Research Initiative launches its TRI Academy online seminar series. The third season of the seminar series will will be launch soon and will be organised every third Wednesday of the month. Each seminar contains of two approximately 20-minute presentations that covers different topics related to tinnitus inclduing definition, risk factors and prevalence, tinnitus mechanisms, treatment options, evidence-based and alternative medicine, e-health and Big Data, and more.
More information: Seminars
The Noise Begins is an app created to promote understanding and provide escape and relief from tinnitus through story, neuroscience, sound and music. In collaboration with Lab CLINT created by actor and writer Dominic Gately from his own lived experience of the condition, it's available now at the App Store.
BRAI3N clinic is implementing new neuromodulation treatments by combining the common neurophysiological mechanisms of diseases, such as the 'thalamocortical dysrhythmia' (tinnitus, pain, Parkinson, depression, epilepsy) and the 'reward deficiency syndromes' (obesity, addiction, obsessive compulsive disorder, ADHD, Autism, Tourette and other "tic" syndromes, personality disorders).BRAI3N clinic is a multidisciplinary and international collaboration between doctors from different disciplines, specialists in neuromodulation, (neuro) psychologists, audiologists, physiotherapists and neuroscientists to aims to implent new scientific insights into the clinic. This way BRAI3N can quickly apply new, scientifically founded treatment protocols.
More information: BRAI3N Clinic